Large-scale genome-wide scans do not support petaloid toenail as a Mendelian trait

Manfei Zhang; Sijie Wu; Juan Zhang; Yajun Yang; Jingze Tan; Haijuan Guan; Yu Liu; Kun Tang; Jean Krutmann; Shuhua Xu; Li Jin; Yaqun Guan; Hui Li; Sijia Wang

doi:10.1016/j.jgg.2016.10.003

Large-scale genome-wide scans do not support petaloid toenail as a Mendelian trait

J Genet Genomics. 2016 Dec 20;43(12):702-704. doi: 10.1016/j.jgg.2016.10.003. Epub 2016 Oct 14.

Authors

Manfei Zhang¹, Sijie Wu², Juan Zhang³, Yajun Yang³, Jingze Tan⁴, Haijuan Guan⁴, Yu Liu², Kun Tang², Jean Krutmann⁵, Shuhua Xu⁶, Li Jin⁷, Yaqun Guan⁸, Hui Li⁹, Sijia Wang¹⁰

Affiliations

¹ Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China; Chinese Academy of Sciences Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
² Chinese Academy of Sciences Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; University of Chinese Academy of Sciences, Beijing 100049, China.
³ Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China; Fudan-Taizhou Institute of Health Sciences, Taizhou 225300, China.
⁴ Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China.
⁵ IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf 40225, Germany.
⁶ Chinese Academy of Sciences Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; University of Chinese Academy of Sciences, Beijing 100049, China; School of Life Science and Technology, Shanghai Tech University, Shanghai 200031, China.
⁷ Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China; Chinese Academy of Sciences Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; Fudan-Taizhou Institute of Health Sciences, Taizhou 225300, China.
⁸ Department of Biochemistry and Molecular Biology, Preclinical Medicine College, Xinjiang Medical University, Urumqi 830011, China. Electronic address: yaqunguan@163.com.
⁹ Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China. Electronic address: LHCA@fudan.edu.cn.
¹⁰ Chinese Academy of Sciences Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China. Electronic address: wangsijia@picb.ac.cn.

PMID: 27964859
DOI: 10.1016/j.jgg.2016.10.003

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Asian People / genetics
China / ethnology
Female
Genome, Human / genetics*
Genome-Wide Association Study*
Genomics
Genotype
Humans
Male
Nails / pathology*
Phenotype