Data describing the association between rs266729 polymorphism inadiponectin promoter gene and Type 2 Diabetes Mellitus

Saiedeh Erfanian; Malihe Moradzadeh; Kavous Solhjoo; Abdolreza Sotoodeh Jahromi

doi:10.1016/j.dib.2016.11.040

Data describing the association between rs266729 polymorphism inadiponectin promoter gene and Type 2 Diabetes Mellitus

Data Brief. 2016 Nov 21:9:1138-1140. doi: 10.1016/j.dib.2016.11.040. eCollection 2016 Dec.

Authors

Saiedeh Erfanian¹, Malihe Moradzadeh², Kavous Solhjoo³, Abdolreza Sotoodeh Jahromi¹

Affiliations

¹ Research Center for Non-Communicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran.
² Department of New Sciences and Technology, Mashhad University of Medical Sciences, Mashhad, Iran.
³ Zoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran.

Abstract

This article investigates whether there is an association between the rs266729 polymorphism in adiponectin promoter gene with metabolic parameters and disease status in 300 type 2 diabetes patients and 300 healthy adults from Jahrom city, Iran. The variants (G/C) were tested by polymerase chain reaction-restriction fragment length polymorphism method (RFLP) and metabolic parameters (glucose, cholesterol, HDL and LDL cholesterol) were measured using biochemical methods. However, no differences were detected between the haplotypes investigated, and the data obtained from our lab shown association of the ADIPOQ promoter polymorphism neither with biochemical parameters, nor with disease status.

Keywords: Adiponectin gene and type 2 diabetes; Polymorphism; rs266729.