Acral manifestations of contact dermatitis

Clin Dermatol. 2017 Jan-Feb;35(1):9-18. doi: 10.1016/j.clindermatol.2016.09.003. Epub 2016 Sep 10.

Abstract

Contact dermatitis is a broad term that encompasses both nonimmunologic irritant contact dermatitis (ICD) and immunologically mediated allergic contact dermatitis (ACD). Both ICD and ACD can negatively affect a patient's quality of life and are a source of exorbitant medical and societal costs. Avoidance of inciting irritants and/or allergens and liberal use of emollients or humectants are the cornerstone of therapy. When an allergic cause is suspected, patch testing is highly encouraged. In this contribution, we highlight both the commonalities and differences of acral contact dermatitis as it relates to specific regions of the body. In addition, a review of the predisposing conditions, risk factors, and treatment options in the literature is presented to help with the care of these challenging patients.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Allergens / adverse effects
  • Calcineurin Inhibitors / therapeutic use
  • Cyclosporine / therapeutic use
  • Dermatitis, Contact / diagnosis
  • Dermatitis, Contact / etiology*
  • Dermatitis, Contact / therapy*
  • Dermatologic Agents / therapeutic use*
  • Ear Diseases / chemically induced
  • Ear Diseases / therapy
  • Foot Dermatoses / etiology
  • Foot Dermatoses / therapy
  • Hand Dermatoses / chemically induced*
  • Hand Dermatoses / diagnosis
  • Hand Dermatoses / therapy*
  • Humans
  • Irritants / adverse effects
  • PUVA Therapy
  • Retinoids / therapeutic use
  • Risk Factors
  • X-Ray Therapy

Substances

  • Adrenal Cortex Hormones
  • Allergens
  • Calcineurin Inhibitors
  • Dermatologic Agents
  • Irritants
  • Retinoids
  • Cyclosporine