Draft genome sequence of a GES-5-producing Serratia marcescens isolated in southern Brazil

Braz J Microbiol. 2017 Apr-Jun;48(2):191-192. doi: 10.1016/j.bjm.2016.08.002. Epub 2016 Nov 23.

Abstract

Serratia marcescens is a Gram-negative rod intrinsically resistant to polymyxins and usually associated with wound, respiratory and urinary tract infections. The whole genome of the first GES-5-producing S. marcescens isolated from a Brazilian patient was sequenced using Ion Torrent PGM System. Besides blaGES-5, we were able to identify genes encoding for other β-lactamases, for aminoglycoside modifying enzymes and for an efflux pump to tetracyclines.

Keywords: GES-5; Serratia marcescens; Whole-genome sequencing.

MeSH terms

  • Brazil
  • DNA, Bacterial / chemistry*
  • DNA, Bacterial / genetics*
  • Genome, Bacterial*
  • Humans
  • Membrane Transport Proteins / genetics
  • Sequence Analysis, DNA*
  • Serratia marcescens / enzymology*
  • Serratia marcescens / genetics*
  • Serratia marcescens / isolation & purification
  • Transferases / metabolism
  • beta-Lactamases / genetics
  • beta-Lactamases / metabolism*

Substances

  • DNA, Bacterial
  • Membrane Transport Proteins
  • Transferases
  • beta-Lactamases