A new diphenyl ether derivative from Mirabilis himalaica

Nat Prod Res. 2017 May;31(9):1034-1041. doi: 10.1080/14786419.2016.1266351. Epub 2016 Dec 8.

Abstract

One new compound, himalain A (1), together with 12 known compounds were isolated from Mirabilis himalaica. Their structures were determined by spectroscopic methods, including 2D NMR techniques, and the absolute configuration of the 1,2-diol moiety in 1 was defined through Riguera's method. All isolated compounds were tested for their cytotoxic and antibacterial activities.

Keywords: Mirabilis himalaica; antibacterial activities; cytotoxic activities; himalain A.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Cell Line, Tumor
  • Humans
  • Mirabilis / chemistry*
  • Phenyl Ethers / chemistry
  • Phenyl Ethers / isolation & purification*
  • Phenyl Ethers / pharmacology

Substances

  • Anti-Bacterial Agents
  • Antineoplastic Agents, Phytogenic
  • Phenyl Ethers