Kounis syndrome and ziprasidone

Am J Emerg Med. 2017 Mar;35(3):493-494. doi: 10.1016/j.ajem.2016.11.061. Epub 2016 Nov 30.

Abstract

Kounis syndrome (KS), described by Kounis and Zavras in 1991, is the manifestation of an allergic reaction preceding and leading to an acute coronary syndrome (ACS). There are three variants of Kounis Syndrome. Here we describe a novel case report of a type 1 variant secondary to Ziprasidone.

Keywords: Allergic reaction; Chest pain; Kounis syndrome; STEMI; Ziprasidone.

Publication types

  • Case Reports

MeSH terms

  • Acute Coronary Syndrome / chemically induced*
  • Acute Coronary Syndrome / immunology*
  • Adult
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use
  • Bipolar Disorder / drug therapy*
  • Drug Hypersensitivity / complications*
  • Emergency Service, Hospital
  • Humans
  • Male
  • Piperazines / adverse effects*
  • Piperazines / therapeutic use
  • Suicidal Ideation*
  • Syndrome
  • Thiazoles / adverse effects*
  • Thiazoles / therapeutic use

Substances

  • Antipsychotic Agents
  • Piperazines
  • Thiazoles
  • ziprasidone