Saturation-inversion-recovery: A method for T1 measurement

Hongzhi Wang; Ming Zhao; Jerome L Ackerman; Yiqiao Song

doi:10.1016/j.jmr.2016.11.015

Saturation-inversion-recovery: A method for T₁ measurement

J Magn Reson. 2017 Jan:274:137-143. doi: 10.1016/j.jmr.2016.11.015. Epub 2016 Nov 27.

Authors

Hongzhi Wang¹, Ming Zhao², Jerome L Ackerman³, Yiqiao Song⁴

Affiliations

¹ Shanghai University of Medicine and Health Science, Shanghai 201318, China; Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai 200062, China; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA. Electronic address: wanghzhi2000@sina.com.
² Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA; Department of Physics, University of Massachusetts Lowell, Lowell, MA 01854, USA.
³ Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA; Harvard Medical School, Boston, MA 02115, USA.
⁴ Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA; Schlumberger-Doll Research, Cambridge, MA 02143, USA.

Abstract

Spin-lattice relaxation (T₁) has always been measured by inversion-recovery (IR), saturation-recovery (SR), or related methods. These existing methods share a common behavior in that the function describing T₁ sensitivity is the exponential, e.g., exp(-τ/T₁), where τ is the recovery time. In this paper, we describe a saturation-inversion-recovery (SIR) sequence for T₁ measurement with considerably sharper T₁-dependence than those of the IR and SR sequences, and demonstrate it experimentally. The SIR method could be useful in improving the contrast between regions of differing T₁ in T₁-weighted MRI.

Keywords: Saturation inversion recovery; Spin-lattice relaxation; T(1) contrast; T(1) dispersion.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Algorithms
Electromagnetic Fields
Image Enhancement / methods*
Image Processing, Computer-Assisted
Magnetic Resonance Imaging / methods*
Signal-To-Noise Ratio
Spectrophotometry, Infrared
Water / chemistry

Substances

Water

Abstract

Publication types

MeSH terms

Substances

Grants and funding