Outbreak of enterovirus D68 of the new B3 lineage in Stockholm, Sweden, August to September 2016

Euro Surveill. 2016 Nov 17;21(46):30403. doi: 10.2807/1560-7917.ES.2016.21.46.30403.

Abstract

We report an enterovirus D68 (EV-D68) outbreak in Stockholm Sweden in 2016. Between 22 August and 25 September EV-D68 was detected in 74/495 respiratory samples analysed at the Karolinska University Hospital. During the peak week, 30/91 (33%) samples were EV-D68 positive. Viral protein (VP)P4/VP2 sequencing revealed that cases were caused by B3 lineage strains. Forty-four (59%) EV-D68-positive patients were children aged ≤ 5 years. Ten patients had severe respiratory or neurological symptoms and one died.

Keywords: VP4/VP2 sequencing; acute flaccid myelitis; enterovirus D68; outbreak; respiratory infection.

MeSH terms

  • Child
  • Child, Preschool
  • Disease Outbreaks*
  • Enterovirus / classification
  • Enterovirus / isolation & purification*
  • Enterovirus D, Human / classification
  • Enterovirus D, Human / genetics*
  • Enterovirus D, Human / isolation & purification*
  • Enterovirus Infections / epidemiology*
  • Enterovirus Infections / virology*
  • Female
  • Genetic Variation*
  • Humans
  • Infant
  • Male
  • Phylogeny
  • Respiratory Tract Infections / epidemiology
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Sweden / epidemiology
  • Viral Structural Proteins / genetics

Substances

  • Viral Structural Proteins