Formin' a Nuclear Protection

Jörg Renkawitz; Michael Sixt

doi:10.1016/j.cell.2016.11.024

Formin' a Nuclear Protection

Cell. 2016 Dec 1;167(6):1448-1449. doi: 10.1016/j.cell.2016.11.024.

Authors

Jörg Renkawitz¹, Michael Sixt²

Affiliations

¹ Institute of Science and Technology Austria (IST Austria), am Campus 1, 3400 Klosterneuburg, Austria.
² Institute of Science and Technology Austria (IST Austria), am Campus 1, 3400 Klosterneuburg, Austria. Electronic address: sixt@ist.ac.at.

PMID: 27912053
DOI: 10.1016/j.cell.2016.11.024

Abstract

In this issue of Cell, Skau et al. show that the formin FMN2 organizes a perinuclear actin cytoskeleton that protects the nucleus and its genomic content of migrating cells squeezing through small spaces.

MeSH terms

Actin Cytoskeleton*
Actins / genetics
Cell Nucleus
Humans
Microfilament Proteins / genetics*

Substances

Actins
Microfilament Proteins