Evolutionary Paradigms from Ancient and Ongoing Conflicts between the Lentiviral Vif Protein and Mammalian APOBEC3 Enzymes

PLoS Pathog. 2016 Dec 1;12(12):e1005958. doi: 10.1371/journal.ppat.1005958. eCollection 2016 Dec.

Authors

Reuben S Harris^{1

2}, Brett D Anderson²

Affiliations

¹ Howard Hughes Medical Institute, University of Minnesota, Minneapolis, Minnesota, United States of America.
² Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Center for Genome Engineering, Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota, United States of America.

No abstract available

Publication types

Research Support, N.I.H., Extramural
Review

MeSH terms

Animals
Biological Evolution
Cytosine Deaminase / metabolism*
Gene Products, vif / genetics
Gene Products, vif / metabolism*
Host-Pathogen Interactions / physiology*
Humans
Lentivirus
Lentivirus Infections / genetics
Lentivirus Infections / metabolism*

Substances

Gene Products, vif
Cytosine Deaminase

Grants and funding