Preventive Salpingectomy and Ovarian Reserve: Experimental Study

Bull Exp Biol Med. 2016 Dec;162(2):255-259. doi: 10.1007/s10517-016-3589-6. Epub 2016 Dec 1.

Abstract

The levels of anti-Müllerian hormone, follicle-stimulating hormone, and testosterone were studied in rats after removal of the uterine horns, oviducts, or combined surgery. The effects of preventive salpingectomy on ovarian reserve were studied. After preventive salpingectomy, the level of anti-Müllerian hormone was low throughout the experiment, follicle-stimulating hormone increased only by the end of observation (on day 40), and testosterone level decreased only on day 10. Hysterectomy alone caused no changes in the concentrations of the studied hormones on day 10 after surgery. Salpingectomy alone reduced the concentrations of anti-Müllerian hormone and testosterone and did not change the level of follicle-stimulating hormone during this period.

Keywords: anti-Müllerian hormone; follicle-stimulating hormone; hysterectomy; ovarian reserve; salpingectomy.

MeSH terms

  • Animals
  • Anti-Mullerian Hormone / blood
  • Anti-Mullerian Hormone / genetics
  • Fallopian Tubes / metabolism
  • Fallopian Tubes / surgery*
  • Female
  • Follicle Stimulating Hormone / blood
  • Follicle Stimulating Hormone / genetics
  • Gene Expression
  • Hysterectomy / methods
  • Ovarian Reserve / genetics*
  • Prophylactic Surgical Procedures*
  • Rats
  • Rats, Wistar
  • Salpingectomy / methods*
  • Testosterone / blood
  • Testosterone / genetics
  • Uterus / metabolism
  • Uterus / surgery*

Substances

  • Testosterone
  • Anti-Mullerian Hormone
  • Follicle Stimulating Hormone