Haloperoxidase Mimicry by CeO2-x Nanorods Combats Biofouling

Karoline Herget; Patrick Hubach; Stefan Pusch; Peter Deglmann; Hermann Götz; Tatiana E Gorelik; Il'ya A Gural'skiy; Felix Pfitzner; Thorben Link; Stephan Schenk; Martin Panthöfer; Vadim Ksenofontov; Ute Kolb; Till Opatz; Rute André; Wolfgang Tremel

doi:10.1002/adma.201603823

Haloperoxidase Mimicry by CeO_2-_x Nanorods Combats Biofouling

Adv Mater. 2017 Jan;29(4). doi: 10.1002/adma.201603823. Epub 2016 Nov 29.

Authors

Karoline Herget¹, Patrick Hubach², Stefan Pusch³, Peter Deglmann⁴, Hermann Götz⁵, Tatiana E Gorelik¹, Il'ya A Gural'skiy^{1

6}, Felix Pfitzner¹, Thorben Link⁷, Stephan Schenk⁴, Martin Panthöfer¹, Vadim Ksenofontov¹, Ute Kolb¹, Till Opatz³, Rute André², Wolfgang Tremel¹

Affiliations

¹ Institut für Anorganische Chemie und Analytische Chemie, Johannes Gutenberg-Universität, Duesbergweg 10-14, D-55128, Mainz, Germany.
² Catalysis Research, Oxidation Catalysis, BASF SE, GCC/PO - M301, D-67056, Ludwigshafen, Germany.
³ Institut für Organische Chemie, Johannes Gutenberg-Universität, Duesbergweg 10-14, D-55128, Mainz, Germany.
⁴ Quantum Chemistry, BASF SE, GME/M - B001, D-67056, Ludwigshafen, Germany.
⁵ Forschungsplattform Biomaterialien, Universitätsmedizin, Johannes Gutenberg-Universität, Obere Zahlbacher Straße 63, D-55131, Mainz, Germany.
⁶ Department of Chemistry, Taras Shevchenko National University of Kyiv, Volodymyrska St. 64, Kyiv, 01601, Ukraine.
⁷ Institut für Physiologische Chemie, Universitätsmedizin, Johannes Gutenberg-Universität, Duesbergweg 6, D-55128, Mainz, Germany.

PMID: 27896889
DOI: 10.1002/adma.201603823

Abstract

CeO_2-_x nanorods are functional mimics of natural haloperoxidases. They catalyze the oxidative bromination of phenol red to bromophenol blue and of natural signaling molecules involved in bacterial quorum sensing. Laboratory and field tests with paint formulations containing 2 wt% of CeO_2-_x nanorods show a reduction in biofouling comparable to Cu₂ O, the most typical biocidal pigment.

Keywords: biofouling; cerium dioxide; enzyme mimic; haloperoxidase; oxidative bromination.