Multi-strip silicon sensors for beam array monitoring in micro-beam radiation therapy

E Alagoz; E Brauer-Krisch; A Bravin; I Cornelius; P Fournier; T E Hansen; A Kok; M Lerch; E Monakhov; J Morse; N Pacifico; M Petasecca; M Povoli; H Requard; A D Rozenfeld; M Salome; H Sandaker; B Stugu

doi:10.1016/j.ejmp.2016.11.005

Multi-strip silicon sensors for beam array monitoring in micro-beam radiation therapy

Phys Med. 2016 Dec;32(12):1795-1800. doi: 10.1016/j.ejmp.2016.11.005. Epub 2016 Nov 24.

Authors

E Alagoz¹, E Brauer-Krisch², A Bravin², I Cornelius³, P Fournier³, T E Hansen⁴, A Kok⁴, M Lerch³, E Monakhov⁵, J Morse², N Pacifico⁶, M Petasecca³, M Povoli⁷, H Requard², A D Rozenfeld³, M Salome², H Sandaker⁵, B Stugu¹

Affiliations

¹ Department of Physics and Technology, University of Bergen, Postboks 7803, N-5020 Bergen, Norway.
² European Synchrotron Radiation Facility, 71 avenue des Martyrs, 38000 Grenoble, France.
³ Centre for Medical Radiation Physics, University of Wollongong, NSW 2522, Australia.
⁴ SINTEF MiNaLab, Department of Microsystems and Nanotechnology, Gaustadalléen 23 C, Oslo, Norway.
⁵ Department of Physics, University of Oslo, Postboks 1048 Blindern, 0316 Oslo, Norway.
⁶ Department of Physics and Technology, University of Bergen, Postboks 7803, N-5020 Bergen, Norway. Electronic address: nicola.pacifico@cern.ch.
⁷ Centre for Material Science and Nanotechnology, University of Oslo, Postboks 1048 Blindern, 0316 Oslo, Norway.

PMID: 27890569
DOI: 10.1016/j.ejmp.2016.11.005

Abstract

We present here the latest results from tests performed at the ESRF ID17 and ID21 beamlines for the characterization of novel beam monitors for Microbeam Radiation Therapy (MRT), which is currently being implemented at ID17. MRT aims at treating solid tumors by exploiting an array of evenly spaced microbeams, having an energy spectrum distributed between 27 and 600keV and peaking at 100keV. Given the high instantaneous dose delivered (up to 20kGy/s), the position and the intensity of the microbeams has to be precisely and instantly monitored. For this purpose, we developed dedicated silicon microstrip beam monitors. We have successfully characterized them, both with a microbeam array at ID17, and a submicron scanning beam at ID21. We present here the latest results obtained in recent tests along with an outlook on future developments.

Keywords: Beam monitor; Micro-beam radiation therapy; Silicon; Synchrotron radiation.

MeSH terms

Equipment Design
Microtechnology / instrumentation*
Radiotherapy / instrumentation*
Radiotherapy Dosage
Silicon*

Substances

Silicon