Influence of Selenium on the Production of T-2 Toxin by Fusarium poae

Biol Trace Elem Res. 2017 Jul;178(1):147-152. doi: 10.1007/s12011-016-0900-3. Epub 2016 Nov 24.

Abstract

The objective of this study was to investigate the effects of selenium on the production of T-2 toxin by a Fusarium poae strain cultured in a synthetic medium containing different concentrations of selenium. The T-2 toxin contents in fermentative products were evaluated by a high performance liquid chromatography (HPLC). The results showed that the production of T-2 toxin was correlated with the concentration of selenium added to the medium. In all three treatments, the addition of 1 mg/L selenium to the medium resulted in a lower toxin yield than the control (0 mg/L); the yield of the toxin began to increase when selenium concentration was 10 mg/L, while it decreased again at 20 mg/L. In summary, T-2 toxin yield in the fermentative product was affected by the addition of selenium to the medium, and a selenium concentration of 20 mg/L produced the maximum inhibitory effect of T-2 toxin yield in the fermentative product of F. poae.

Keywords: Fusarium poae; Kashin-Beck disease; Selenium; T-2 toxin.

MeSH terms

  • Dose-Response Relationship, Drug
  • Fusarium / metabolism*
  • Selenium / pharmacology*
  • T-2 Toxin / biosynthesis*

Substances

  • Selenium
  • T-2 Toxin