The effect of Daikenchuto on postoperative intestinal motility in patients with right-side colon cancer

Surg Today. 2017 Jul;47(7):865-871. doi: 10.1007/s00595-016-1449-7. Epub 2016 Nov 21.

Abstract

Purpose: Daikenchuto (DKT) has a stimulant effect on intestinal motility and reportedly has a positive effect on postoperative intestinal motility in patients with sigmoid colon cancer. In this study, we investigated the effects of DKT in patients with right-side colon cancer.

Methods: This retrospective study included 88 patients with right-side colon cancer. We orally administered 7.5 g of DKT in the DKT group and did not administer any DKT to patients in the no-DKT group. All patients ingested radiopaque markers 2 h before surgery, which were used to assess intestinal motility. The postoperative intestinal motility was radiologically assessed by counting the numbers of residual markers in the large and small intestines.

Results: The DKT and no-DKT groups showed no marked differences in the total number of residual markers or number of residual markers in the small intestine. However, in the elderly subgroup, the total number of residual markers in the DKT group was significantly less than in the no-DKT group.

Conclusion: Although DKT had some small effect on the postoperative intestinal motility for most patients, it may have positive effects in elderly patients.

Keywords: Colon cancer; Daikenchuto; Enhanced recovery after surgery.

MeSH terms

  • Administration, Oral
  • Adult
  • Aged
  • Aged, 80 and over
  • Colonic Neoplasms / physiopathology*
  • Colonic Neoplasms / surgery*
  • Female
  • Gastrointestinal Motility*
  • Humans
  • Ileus / prevention & control*
  • Male
  • Middle Aged
  • Panax
  • Perioperative Care
  • Phytotherapy*
  • Plant Extracts / administration & dosage*
  • Plant Extracts / pharmacology*
  • Postoperative Complications / prevention & control*
  • Postoperative Period
  • Retrospective Studies
  • Zanthoxylum
  • Zingiberaceae

Substances

  • Plant Extracts
  • dai-kenchu-to