Buzz Juice: Neurological sequelae of synthetic cannabinoids

Manisha Kak; Fadi Mikhail; Sho T Yano; Rui Guan; Rimas V Lukas

doi:10.1016/j.jocn.2016.10.046

Buzz Juice: Neurological sequelae of synthetic cannabinoids

J Clin Neurosci. 2017 Mar:37:43. doi: 10.1016/j.jocn.2016.10.046. Epub 2016 Nov 16.

Authors

Manisha Kak¹, Fadi Mikhail², Sho T Yano³, Rui Guan⁴, Rimas V Lukas⁴

Affiliations

¹ University of Chicago, Department of Neurology, United States. Electronic address: manisha.kak@uchospitals.edu.
² University of Pennsylvania, Department of Neurology, United States.
³ University of Chicago, Department of Neurology, United States; University of Chicago, Department of Pediatrics, Section of Pediatric Neurology, United States.
⁴ University of Chicago, Department of Neurology, United States.

PMID: 27865819
DOI: 10.1016/j.jocn.2016.10.046

Abstract

The use of synthetic cannabinoids is becoming more widespread. Familiarity with the potential toxicities associated with these agents will grow in importance. We present a case of a woman who developed onset of confusion, visual hallucinations, and ataxia after vaporizing synthetic cannabinoids. MRI imaging demonstrated restricted diffusion and increased T2/FLAIR signal in the corpus callosum and cerebellar peduncles.

Keywords: Buzz Juice; Corpus callosum; Encephalopathy; MRI; Neurological symptoms; Synthetic marijuana.

MeSH terms

Adult
Ataxia / chemically induced
Ataxia / diagnostic imaging
Brain / diagnostic imaging*
Brain / drug effects
Cannabinoids / adverse effects*
Cannabinoids / pharmacology
Confusion / chemically induced
Confusion / diagnostic imaging
Consciousness Disorders / chemically induced
Consciousness Disorders / diagnostic imaging
Female
Humans
Leukoencephalopathies / chemically induced*
Leukoencephalopathies / diagnostic imaging
Magnetic Resonance Imaging
Multiple Organ Failure / chemically induced*
Multiple Organ Failure / diagnostic imaging

Substances

Cannabinoids