The Chorioallantoic Membrane of the Chick Embryo to Assess Tumor Formation and Metastasis

Anne Herrmann; Diana Moss; Violaine Sée

doi:10.1007/978-1-4939-3999-2_9

The Chorioallantoic Membrane of the Chick Embryo to Assess Tumor Formation and Metastasis

Methods Mol Biol. 2016:1464:97-105. doi: 10.1007/978-1-4939-3999-2_9.

Authors

Anne Herrmann^{1

2}, Diana Moss², Violaine Sée³

Affiliations

¹ Department of Biochemistry, University of Liverpool, Biosciences Bldg., Liverpool, L69 7ZB, UK.
² Department of Cellular and Molecular Physiology, University of Liverpool, Liverpool, L69 3BX, UK.
³ Department of Biochemistry, University of Liverpool, Biosciences Bldg., Liverpool, L69 7ZB, UK. violaine@liverpool.ac.uk.

PMID: 27858359
DOI: 10.1007/978-1-4939-3999-2_9

Abstract

The chorioallantoic membrane (CAM) of the chick embryo is a suitable and convenient platform for the assessment of tumor formation and metastatic dissemination. Here, we describe tumor cell engraftment on the extraembryonic CAM and further monitoring of tumor growth and metastasis.

Keywords: CAM; Chick embryo; Metastasis; Tumor model; Tumorigenesis.

MeSH terms

Animals
Carcinogenesis / pathology*
Cell Line, Tumor
Chick Embryo
Chorioallantoic Membrane / pathology*
Humans
Models, Biological
Neoplasm Metastasis