This article draws attention to the relationship between neuroethics, neuropolitics, political psycho-cultures and public and global mental health. In the hegemonic culture of neoliberalism the purpose of life has been reduced to the self-realization in economic and consumerism terms that promotes the hypercompetitive narcissistic or manic self, indifferent to the fate and suffering of others and accommodated to commodification of morals, mental health and well-being. The real public and global mental health promotion is strongly associated with creating a more empathic, less selfish individual and collective mind where people put a greater emphasis on common interests and bioethical values.