Efforts to improve care of patients with ESRD and the policies that guide those activities depend on evidence-based best practices derived from clinical trials and carefully conducted observational studies. Our review describes this process in the context of the translational research model (bench to bedside to populations), with a particular emphasis on bedside care. We illustrate some of its accomplishments and describe the limitations of the data and evidence supporting policy and practice.
Keywords: Chronic; Epidemiology and outcomes; Humans; Kidney Failure; Medical Research; Public Policy; Quality improvement; Renal Insufficiency; Translational; Translational epidemiology; guidelines; nephrology; policy; surveillance.
Copyright © 2016 by the American Society of Nephrology.