Hematopoietic stem cell transplant in patients with activated PI3K delta syndrome

Zohreh Nademi; Mary A Slatter; Christopher C Dvorak; Benedicte Neven; Alain Fischer; Felipe Suarez; Claire Booth; Kanchan Rao; Alexandra Laberko; Julia Rodina; Yves Bertrand; Sylwia Kołtan; Robert Dębski; Terence Flood; Mario Abinun; Andrew R Gennery; Sophie Hambleton; Stephan Ehl; Andrew J Cant

doi:10.1016/j.jaci.2016.09.040

Hematopoietic stem cell transplant in patients with activated PI3K delta syndrome

J Allergy Clin Immunol. 2017 Mar;139(3):1046-1049. doi: 10.1016/j.jaci.2016.09.040. Epub 2016 Nov 12.

Authors

Zohreh Nademi¹, Mary A Slatter², Christopher C Dvorak³, Benedicte Neven⁴, Alain Fischer⁴, Felipe Suarez⁵, Claire Booth⁶, Kanchan Rao⁷, Alexandra Laberko⁸, Julia Rodina⁸, Yves Bertrand⁹, Sylwia Kołtan¹⁰, Robert Dębski¹⁰, Terence Flood¹¹, Mario Abinun², Andrew R Gennery², Sophie Hambleton², Stephan Ehl¹², Andrew J Cant²

Affiliations

¹ Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle upon Tyne University, Newcastle upon Tyne, United Kingdom. Electronic address: zohreh.nademi@nuth.nhs.uk.
² Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle upon Tyne University, Newcastle upon Tyne, United Kingdom.
³ Benioff Children's Hospital, University of California San Francisco, San Francisco, Calif.
⁴ Pediatric Hematology-Immunology and Rheumatology Unit, Necker-Enfants Malades University Hospital, Paris, France.
⁵ Department of Hematology, Necker-Enfants Malades University Hospital, Paris, France.
⁶ Department of Pediatric Immunology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
⁷ Department of Bone Marrow Transplant, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
⁸ Center for Pediatric Hematology, Oncology, Immunology, Moscow, Russia.
⁹ Institut d'Hématologie et d'Oncologie pédiatrique (Hospices Civils de Lyon) et Université Claude Bernard Lyon, Lyon, France.
¹⁰ Department of Pediatric, Hematology and Oncology, Collegium Medicum Bydgoszcz, Nicolaus Copernicus University, Toruń, Poland.
¹¹ Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
¹² Center for Chronic Immunodeficiency, University of Freiburg Medical Center, Freiburg, Germany.

PMID: 27847301
DOI: 10.1016/j.jaci.2016.09.040

No abstract available

Publication types

Letter

MeSH terms

Adolescent
Child
Child, Preschool
Class I Phosphatidylinositol 3-Kinases
Female
Hematopoietic Stem Cell Transplantation / methods*
Humans
Immunologic Deficiency Syndromes / therapy*
Male
Primary Immunodeficiency Diseases

Substances

Class I Phosphatidylinositol 3-Kinases

Supplementary concepts

Activated PI3K-delta Syndrome