Droplet-like heterogeneity of aqueous tetrahydrofuran solutions at the submicrometer scale

N F Bunkin; A V Shkirin; G A Lyakhov; A V Kobelev; N V Penkov; S V Ugraitskaya; E E Fesenko Jr

doi:10.1063/1.4966187

Droplet-like heterogeneity of aqueous tetrahydrofuran solutions at the submicrometer scale

J Chem Phys. 2016 Nov 14;145(18):184501. doi: 10.1063/1.4966187.

Authors

N F Bunkin¹, A V Shkirin², G A Lyakhov², A V Kobelev³, N V Penkov³, S V Ugraitskaya³, E E Fesenko Jr³

Affiliations

¹ Bauman State Technical University, 2nd Baumanskaya ul. 5, Moscow 105005, Russia.
² Prokhorov General Physics Institute, Russian Academy of Sciences, ul. Vavilova 38, Moscow 119991, Russia.
³ Institute of Cell Biophysics, Russian Academy of Sciences, ul. Institutskaya 3, Pushchino, Moscow Region 142290, Russia.

PMID: 27846700
DOI: 10.1063/1.4966187

Abstract

A droplet formation in aqueous solutions of tetrahydrofuran (THF) has been experimentally detected at the submicrometer scale using two independent laser diagnostic techniques (dynamic light scattering and laser phase microscopy) and described in terms of THF-water intermolecular hydrogen bonding. It is shown that the nanodroplets have a mean size of 300 nm, their refractive index is higher than that of the ambient liquid, and they are highly enriched with THF molecules. The maximum of light scattering intensity falls within the THF concentration range 2-8 mol. %, which corresponds to the volume number density of the nanodroplets ∼10¹⁰-10¹¹ cm^-3. A theoretical explanation of forming the nanodroplets with a high content of THF, which is based on a model of dichotomous noise being applied to the so-termed "twinkling" hydrogen bonds and involves spinodal decomposition in the unstable region enclosed within the dichotomous binodal, is proposed. The parameters of hydrogen bonds in the molecular system "water-THF" were found, and the phase diagram of the solution with allowance for cross-linking hydrogen bonds was constructed.