Focal therapy in prostate cancer: A review of seven common controversies

Edward J Bass; Hashim U Ahmed

doi:10.1016/j.ctrv.2016.07.004

Focal therapy in prostate cancer: A review of seven common controversies

Cancer Treat Rev. 2016 Dec:51:27-34. doi: 10.1016/j.ctrv.2016.07.004. Epub 2016 Jul 18.

Authors

Edward J Bass¹, Hashim U Ahmed²

Affiliations

¹ Division of Surgery and Interventional Science, UCL, London, UK; Department of Urology, UCLH NHS Foundation Trust, London, UK. Electronic address: E.bass@ucl.ac.uk.
² Division of Surgery and Interventional Science, UCL, London, UK; Department of Urology, UCLH NHS Foundation Trust, London, UK.

PMID: 27846402
DOI: 10.1016/j.ctrv.2016.07.004

Abstract

Radical treatments such as prostatectomy and radiotherapy have demonstrated success in terms of biochemical and disease-specific survival for localised prostate cancer. However, whilst the end goal of any cancer treatment is to control or cure disease it must also do so by minimising any side effects that may be experienced by the patient. Focal therapy as a concept aims to redress this established therapeutic ratio by treating areas of the prostate affected by significant disease as opposed to treating the entire gland. However, there are a number of common criticisms of focal therapy - we deem the seven sins - that require further interrogation.

Keywords: Arguments against; Arguments for; Focal therapy; Prostate cancer.

Publication types

Review

MeSH terms

Humans
Male
Prostatic Neoplasms / radiotherapy
Prostatic Neoplasms / surgery
Prostatic Neoplasms / therapy*

Abstract

Publication types

MeSH terms

Grants and funding