Liposomes Came First: The Early History of Liposomology

Methods Mol Biol. 2017:1522:1-15. doi: 10.1007/978-1-4939-6591-5_1.

Abstract

It has been a long journey from Pliny the Elder (23-79 AD) to the FDA approval of the first injectable Nanomedicine in 1997. It has been a journey powered by intellectual curiosity, which began with sprinkling olive oil on seawater and culminated in playing around with smears of egg lecithin on microscopic slides. This brief review highlights how a few pairs of gifted hands attached to highly motivated brains have launched Liposome Technology.

Keywords: Biological membranes; Drug delivery; Liposomes; Membrane models; Phospholipids.

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Delivery Systems
  • Humans
  • Liposomes / metabolism*
  • Membranes, Artificial

Substances

  • Liposomes
  • Membranes, Artificial