Auditory brain stem response and cortical evoked potentials in children with type 1 diabetes mellitus

Acta Otolaryngol. 2017 May;137(5):511-515. doi: 10.1080/00016489.2016.1252059. Epub 2016 Nov 11.

Abstract

Conclusions: Delay in ABR and CAEPs wave latencies in children with type 1DM indicates that there is abnormality in the neural conduction in DM patients. The duration of DM has greater effect on auditory function than the control of DM.

Background: Diabetes mellitus (DM) is a common endocrine and metabolic disorder. Evoked potentials offer the possibility to perform a functional evaluation of neural pathways in the central nervous system.

Objectives: To investigate the effect of type 1 diabetes mellitus (T1DM) on auditory brain stem response (ABR) and cortical evoked potentials (CAEPs).

Method: This study included two groups: a control group (GI), which consisted of 20 healthy children with normal peripheral hearing, and a study group (GII), which consisted of 30 children with type I DM. Basic audiological evaluation, ABR, and CAEPs were done in both groups.

Results: Delayed absolute latencies of ABR and CAEPs waves were found. Amplitudes showed no significant difference between both groups. Positive correlation was found between ABR wave latencies and duration of DM. No correlation was found between ABR, CAEPs, and glycated hemoglobin.

Keywords: Auditory evoked potentials; auditory brain stem response; cortical auditory evoked potentials; diabetes mellitus.

MeSH terms

  • Adolescent
  • Case-Control Studies
  • Child
  • Diabetes Mellitus, Type 1 / physiopathology*
  • Evoked Potentials, Auditory, Brain Stem*
  • Female
  • Humans
  • Male