Abstract
Two new sesquiterpene glycosides, namely massonside A (1) and massonside B (2), were isolated from the n-Bu extract of the fresh needles of Pinus massoniana Lamb. Their structures were established by 1D, 2D nuclear magnetic resonance and high-resolution mass spectrometry. Their biological activities were profiled by the anti-HBV and anti-HCV assays.
Keywords:
HBV; HCV; Pinus massoniana Lamb.; fresh needles; massonside A; massonside B; sesquiterpene glycosides.
MeSH terms
-
Antiviral Agents / chemistry
-
Antiviral Agents / isolation & purification
-
Glycosides / chemistry
-
Glycosides / isolation & purification
-
Glycosides / pharmacology*
-
Hepacivirus / drug effects
-
Hepatitis B virus / drug effects
-
Humans
-
Molecular Structure
-
Pinus / chemistry*
-
Plant Extracts / chemistry
-
Plant Leaves / chemistry
-
Sesquiterpenes / chemistry
-
Sesquiterpenes / isolation & purification
-
Sesquiterpenes / pharmacology*
-
Spectrum Analysis
Substances
-
Antiviral Agents
-
Glycosides
-
Plant Extracts
-
Sesquiterpenes