Gastrointestinal hormones and the gut connectome

Curr Opin Endocrinol Diabetes Obes. 2017 Feb;24(1):9-14. doi: 10.1097/MED.0000000000000299.

Abstract

Purpose of review: Provision of adequate nutrients by the gut is essential for survival and essential behaviors are linked to the proper ingestion and digestion of food. Recently, a new neural connection has been reported between sensory cells of the gut epithelium and the nervous system that mediates signals from the gut to the brain.

Recent findings: This review describes how the gut senses its environment, relays those signals to the brain, and how the brain influences the gut.

Summary: This gut-brain connection provides a pathway for how the body handles food.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / physiology*
  • Connectome*
  • Digestion / physiology
  • Eating
  • Enteroendocrine Cells / physiology
  • Gastrointestinal Hormones / physiology*
  • Gastrointestinal Microbiome / physiology
  • Gastrointestinal Tract / innervation
  • Gastrointestinal Tract / physiology*
  • Humans

Substances

  • Gastrointestinal Hormones