Optical fibre sensors: their role in in vivo dosimetry for prostate cancer radiotherapy

Cancer Nanotechnol. 2016;7(1):7. doi: 10.1186/s12645-016-0020-y. Epub 2016 Oct 18.

Abstract

Review is made of dosimetric studies of current optical fibre technology in radiotherapy for therapeutic applications, focusing particularly on in vivo dosimetry for prostate radiotherapy. We present the various sensor designs along with the main advantages and disadvantages associated with this technology. Optical fibres are ideally placed for applications in radiotherapy dosimetry; due to their small size they are lightweight and immune to electromagnetic interferences. The small dimensions of optical fibres allows it to be easily guided within existing brachytherapy equipment; for example, within the seed implantation needle for direct tumour dose analysis, in the urinary catheter to monitor urethral dose, or within the biopsy needle holder of the transrectal ultrasound probe to monitor rectal wall dose. The article presents the range of optical fibre dosimeter designs along with the main dosimetric properties required for a modern in vivo dosimetry system to be utilised in a clinical environment.

Keywords: Brachytherapy; Dosimetry; Optical fibre; Radiation sensor; Radioluminescence; Radiotherapy.

Publication types

  • Review