A plasmonic multi-logic gate platform based on sequence-specific binding of estrogen receptors and gold nanorods

Roger M Pallares; Michel Bosman; Nguyen T K Thanh; Xiaodi Su

doi:10.1039/c6nr07569j

A plasmonic multi-logic gate platform based on sequence-specific binding of estrogen receptors and gold nanorods

Nanoscale. 2016 Dec 8;8(48):19973-19977. doi: 10.1039/c6nr07569j.

Authors

Roger M Pallares¹, Michel Bosman², Nguyen T K Thanh³, Xiaodi Su²

Affiliations

¹ Department of Chemistry, University College London, London, WC1H 0AJ, UK and Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), 2 Fusionopolis Way. Innovis, #8-03, Singapore138634. xd-su@imre.a-star.edu.sg.
² Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), 2 Fusionopolis Way. Innovis, #8-03, Singapore138634. xd-su@imre.a-star.edu.sg.
³ Biophysics Group, Department of Physics and Astronomy, University College London, London, WC1E 6BT, UK and UCL Healthcare Biomagnetic and Nanomaterials Laboratories, 21 Albemarle Street, London W1S 4BS, UK. ntk.thanh@ucl.ac.uk.

PMID: 27783084
DOI: 10.1039/c6nr07569j

Abstract

A hybrid system made of gold nanorods (AuNRs) and double-stranded DNA (dsDNA) is used to build a versatile multi-logic gate platform, capable of performing six different logic operations. The sequence-specific binding of transcription factors to the DNA drives the optical response of the design.

MeSH terms

DNA*
Gold*
Humans
Logic
Nanotubes*
Receptors, Estrogen / chemistry*
Surface Plasmon Resonance*

Substances

Receptors, Estrogen
Gold
DNA