A Randomised Controlled Trial to Test the Effectiveness of Planning Strategies to Improve Medication Adherence in Patients with Cardiovascular Disease

Appl Psychol Health Well Being. 2017 Mar;9(1):106-129. doi: 10.1111/aphw.12081. Epub 2016 Oct 25.

Abstract

Background: Low levels of adherence to medication prescribed to treat and manage chronic disease may lead to maladaptive health outcomes. Theory-based, easy-to-administer interventions that promote patients' effective self-regulation of their medication-taking behaviour are needed if adherence is to be maximised. We tested the effectiveness of an intervention adopting planning techniques to promote medication adherence.

Methods: Outpatients with cardiovascular disease (N = 71) were allocated to either an experimental condition, in which participants were asked to form implementation intentions and coping plans related to their treatment, or to a no-planning control condition, in which participants received no treatment. Patients also completed self-report measures of medication adherence, self-efficacy, and beliefs in medication necessity and concerns. Measures were administered at baseline and at 6-week follow-up.

Results: Results revealed no overall main effect for the intervention on medication adherence. Post-hoc moderator analyses revealed that the intervention was effective in patients with lower necessity beliefs compared to those with higher necessity beliefs.

Conclusion: While current findings have promise in demonstrating the conditional effects of planning interventions, there is a need to replicate these findings by manipulating planning and beliefs independently and testing their direct and interactive effects on medication adherence.

Keywords: behaviour change intervention; cardiovascular disease; coping planning; implementation intention; medication adherence.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adaptation, Psychological
  • Cardiovascular Diseases / psychology
  • Cardiovascular Diseases / therapy*
  • Female
  • Health Knowledge, Attitudes, Practice*
  • Health Promotion / methods*
  • Humans
  • Intention
  • Male
  • Medication Adherence / psychology*
  • Medication Adherence / statistics & numerical data*
  • Middle Aged
  • Motivation
  • Program Evaluation / statistics & numerical data*