Leukemic infiltration presenting as myocardial hypertrophy after complete remission of acute myeloid leukemia

Echocardiography. 2017 Jan;34(1):136-138. doi: 10.1111/echo.13404. Epub 2016 Oct 25.

Abstract

Here, we report a rare case of isolated leukemic infiltrate of the myocardium (extramedullary involvement) presenting as restrictive cardiomyopathy in a patient in complete remission of acute myeloid leukemia. It was evaluated with multimodality imaging studies (echocardiography and cardiac MRI) and further confirmed by pathology. The present case highlights the importance of maintaining a high degree of clinical suspicion when evaluating patients with progressive ventricular hypertrophy of unknown cause, including recognition of the potential involvement by recurrent hematologic malignancy.

Keywords: echocardiography; left ventricular hypertrophy; leukemia; restrictive cardiomyopathy.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Cardiomyopathy, Restrictive / diagnosis*
  • Cardiomyopathy, Restrictive / etiology
  • Echocardiography / methods*
  • Humans
  • Hypertrophy
  • Leukemia, Myeloid, Acute / complications*
  • Leukemic Infiltration / diagnosis*
  • Magnetic Resonance Imaging, Cine / methods
  • Male
  • Middle Aged
  • Myocardium / pathology*
  • Remission Induction