Overview of the Novel and Improved Pulmonary Ventilation-Perfusion Imaging Applications in the Era of SPECT/CT

Saeed Elojeimy; Irene Cruite; Stephen Bowen; Jing Zeng; Hubert Vesselle

doi:10.2214/AJR.15.15071

Overview of the Novel and Improved Pulmonary Ventilation-Perfusion Imaging Applications in the Era of SPECT/CT

AJR Am J Roentgenol. 2016 Dec;207(6):1307-1315. doi: 10.2214/AJR.15.15071. Epub 2016 Oct 11.

Authors

Saeed Elojeimy¹, Irene Cruite², Stephen Bowen³, Jing Zeng³, Hubert Vesselle²

Affiliations

¹ 1 Department of Radiology, University of New Mexico, Albuquerque, NM.
² 2 Department of Radiology, University of Washington Medical Center, 1959 NE Pacific St, Seattle, WA 98195.
³ 3 Department of Radiation Oncology, University of Washington Medical Center, Seattle, WA.

PMID: 27726408
DOI: 10.2214/AJR.15.15071

Abstract

Objective: In this article, we describe the concepts of ventilation-perfusion planar, SPECT, and SPECT/CT and outline the advantages of integrated ventilation-perfusion SPECT/CT over planar imaging. We present an overview of the traditional and new applications of ventilation-perfusion scintigraphy.

Conclusion: SPECT/CT has improved the diagnostic accuracy of ventilation-perfusion imaging and opened the door for a new spectrum of applications.

Keywords: SPECT; SPECT/CT; perfusion; planar; pulmonary; ventilation.

Publication types

Review

MeSH terms

Administration, Inhalation
Humans
Image Enhancement / methods*
Image Interpretation, Computer-Assisted / methods
Lung Diseases / diagnostic imaging*
Radiopharmaceuticals / administration & dosage*
Reproducibility of Results
Respiration Disorders / diagnostic imaging*
Sensitivity and Specificity
Single Photon Emission Computed Tomography Computed Tomography / instrumentation
Single Photon Emission Computed Tomography Computed Tomography / methods*
Ventilation-Perfusion Ratio*

Substances

Radiopharmaceuticals