A meta-analysis of contrast-enhanced computer tomography in the diagnosis of colorectal cancer

J Cancer Res Ther. 2016 Oct;12(Supplement):79-81. doi: 10.4103/0973-1482.191639.

Abstract

Objective: To investigate the diagnostic value of contrast-enhanced computer tomography in diagnosis of colorectal cancer.

Methods: All the diagnostic studies about contrast-enhanced computer tomography in diagnosis of colorectal cancer were searched in the PubMed, Medline, EMBASE, CNKI, and Wanfang databases and included in this meta-analysis. The diagnostic sensitivity and specificity were pooled. The data were analyzed by statistic software Meta-DiSc1.4.

Results: After searching the databases, eight studies with 4764 cases were finally included in this meta-analysis. The combined results showed the pooled diagnostic sensitivity and specificity were 0.73 (95% confidence interval [CI] of 0.69-0.76) and 0.86 (95% CI of 0.85-0.87). Moreover, the area under the receiver operating characteristic was 0.896.

Conclusion: Contrast-enhanced computer tomography was a good method for detection colorectal cancer.

Publication types

  • Meta-Analysis

MeSH terms

  • Colorectal Neoplasms / diagnostic imaging*
  • Contrast Media
  • Humans
  • ROC Curve
  • Radiographic Image Enhancement*
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed / methods*

Substances

  • Contrast Media