Imaging of Idiopathic Pulmonary Fibrosis

Joanna E Kusmirek; Maria Daniela Martin; Jeffrey P Kanne

doi:10.1016/j.rcl.2016.05.004

Imaging of Idiopathic Pulmonary Fibrosis

Radiol Clin North Am. 2016 Nov;54(6):997-1014. doi: 10.1016/j.rcl.2016.05.004.

Authors

Joanna E Kusmirek¹, Maria Daniela Martin², Jeffrey P Kanne²

Affiliations

¹ Department of Radiology, Virginia Commonwealth University, 1250 East Marshall Street, Richmond, VA 23298, USA. Electronic address: joanna.kusmirek@vcuhealth.org.
² Department of Radiology, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792-3252, USA.

PMID: 27719984
DOI: 10.1016/j.rcl.2016.05.004

Abstract

Idiopathic interstitial pneumonias are a heterogeneous group of diffuse lung diseases characterized by distinct clinicopathologic entities with the usual interstitial pneumonia (UIP) being the most common. The pattern of UIP can be seen in idiopathic pulmonary fibrosis (IPF) as well as in secondary causes, most commonly in connective tissue diseases. IPF is usually progressive and associated with a very poor prognosis, and newer therapies pose a risk of serious complications; therefore, diagnostic certainty is crucial. This article reviews the radiologic findings in UIP with clinical correlation and histopathologic features along with its significance for prognosis and patients monitoring.

Keywords: HRCT; Idiopathic interstitial pneumonia; Idiopathic pulmonary fibrosis; Usual interstitial pneumonia.

Publication types

Review

MeSH terms

Diagnosis, Differential
Evidence-Based Medicine
Humans
Idiopathic Pulmonary Fibrosis / diagnostic imaging*
Pulmonary Alveoli / diagnostic imaging*
Radiographic Image Enhancement / methods*
Radiography, Thoracic / methods*
Rare Diseases / diagnostic imaging
Tomography, X-Ray Computed / methods*