Risk Groups for Survival in HPV-Positive and HPV-Negative OPSCC

Michelle M Rietbergen; Ruud H Brakenhoff; C René Leemans

doi:10.1007/978-3-319-43580-0_17

Risk Groups for Survival in HPV-Positive and HPV-Negative OPSCC

Recent Results Cancer Res. 2017:206:221-231. doi: 10.1007/978-3-319-43580-0_17.

Authors

Michelle M Rietbergen¹, Ruud H Brakenhoff¹, C René Leemans²

Affiliations

¹ Department of Otolaryngology/Head and Neck Surgery, VU University Medical Center, Amsterdam, The Netherlands.
² Department of Otolaryngology/Head and Neck Surgery, VU University Medical Center, Amsterdam, The Netherlands. cr.leemans@vumc.nl.

PMID: 27699542
DOI: 10.1007/978-3-319-43580-0_17

Abstract

Over the last three decades, it has become clear that infection with high-risk human papillomavirus (HPV) is etiologically linked to the development of head and neck squamous cell carcinomas, particularly those carcinomas that arise in the oropharyngeal region.

Keywords: Biomarkers; Comorbidity; De-escalation; Prognostic model; Risk groups.

Publication types

Review

MeSH terms

Carcinoma, Squamous Cell / mortality*
Carcinoma, Squamous Cell / virology*
Head and Neck Neoplasms / mortality*
Head and Neck Neoplasms / virology*
Humans
Papillomaviridae / pathogenicity
Papillomavirus Infections / mortality*
Papillomavirus Infections / virology
Squamous Cell Carcinoma of Head and Neck