Nonalcoholic fatty liver disease, association with cardiovascular disease and treatment. (I). Nonalcoholic fatty liver disease and its association with cardiovascular disease

Clin Investig Arterioscler. 2017 May-Jun;29(3):141-148. doi: 10.1016/j.arteri.2016.06.003. Epub 2016 Sep 28.
[Article in English, Spanish]

Abstract

Non-alcoholic fatty liver disease (NAFLD) comprises a series of histologically lesions similar to those induced by alcohol consumption in people with very little or no liver damage. The importance of NAFLD is its high prevalence in the Western world and, from the point of view of the liver, in its gradual progression from steatosis to steatohepatitis, cirrhosis, and liver cancer. During the last decade it has been observed that NAFLD leads to an increased cardiovascular risk with acceleration of arteriosclerosis and events related to it, being the main cause of its morbidity and mortality. This review, updated to January 2016, consists of two parts, with the first part analysing the association of NAFLD with cardiovascular disease.

Keywords: Arteriosclerosis; Atherosclerosis; Cardiovascular diseases; Cardiovascular risk; Enfermedad del hígado graso no alcohólica; Enfermedades cardiovasculares; Esteatohepatitis no alcohólica; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Riesgo cardiovascular; Tratamiento; Treatment.

Publication types

  • Review

MeSH terms

  • Atherosclerosis / etiology*
  • Atherosclerosis / mortality
  • Cardiovascular Diseases / etiology*
  • Cardiovascular Diseases / mortality
  • Disease Progression
  • Humans
  • Non-alcoholic Fatty Liver Disease / complications*
  • Non-alcoholic Fatty Liver Disease / mortality
  • Non-alcoholic Fatty Liver Disease / physiopathology
  • Risk Factors