Are click-evoked BAEPs useful in case of neonate hyperbilirubinemia?

Int J Pediatr Otorhinolaryngol. 1989 Jul;17(3):231-7. doi: 10.1016/0165-5876(89)90050-5.

Abstract

There is still controversy about the usefulness of click-evoked brainstem auditory evoked potentials (BAEPs) for the investigation of neonatal hyperbilirubinemia. The present work concerns the study of click-evoked BAEP responses in a population of 72 hyperbilirubinemic children (conceptional age between 33 and 42 weeks). Their bilirubinemia rates were between 219 and 600 mumol/l. The waves I, III and V were always present, and click BAEP thresholds were normal in all subjects. Latency anomalies were found only for 8 of the 72 subjects. The comparison of subjects having the higher (greater than 307 mumol/l) bilirubin levels with the group having the lower ones failed to show any significant differences for the I-III and I-V intervals. The influence of prematurity in BAEP alteration has not been demonstrated in this study. These data show, on the one hand, normal click-BAEP thresholds but, on the other hand, alterations of central conduction time in some hyperbilirubinemic newborns. It seems that other factors than hyperbilirubinemia might be operating.

Publication types

  • Comparative Study

MeSH terms

  • Acoustic Stimulation
  • Auditory Threshold*
  • Bilirubin / blood*
  • Brain Stem / physiology
  • Evoked Potentials, Auditory*
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Jaundice, Neonatal / blood
  • Jaundice, Neonatal / physiopathology*
  • Male
  • Reaction Time

Substances

  • Bilirubin