Influence of change in surgical practice for benign thyroid disease on postsurgical outcome-Single-center experience in 1400 patients

Asian J Surg. 2018 Jan;41(1):39-46. doi: 10.1016/j.asjsur.2016.07.015. Epub 2016 Sep 19.

Abstract

Purpose: To evaluate the rate of surgical complications during the change from subtotal resection to hemithyroidectomy or thyroidectomy over a period of 17 years.

Methods: All operations for benign goiter at our hospital were analyzed for the periods 1996-2002 (Group 1) and 2003-2012 (Group 2). The groups were compared for recurrent laryngeal nerve damage, hypocalcemia, and other surgical complications directly postoperatively.

Results: In total, 1462 patients were operated on for goiter between 1996 and 2012. There were 1219 patients who underwent a primary thyroid operation, whereas 50 patients had surgery for recurrence. Postoperative histology revealed thyroid cancer in 193 patients (13.2%). In Group 1, 42.7% of all operated lobes were performed as lobectomies and 57.3% as subtotal resections; in Group 2, 74.4% were performed as lobectomies and 25.6% as subtotal resections. No differences were found for reduced vocal cord function (2.4% vs. 1.9%, p = 0.746) and recurrent laryngeal nerve paralysis in the postoperative laryngoscopy (2.9% vs. 1.8%, p = 0.675). Postoperative hypoparathyroidism was detected in 13.66% in Group 1 and in 19.80% in Group 2 after bilateral resections (p = 0.037). There was no difference in the rate of reoperations for cancer between both groups (43.4% vs. 52.1%, p = 0.182).

Conclusion: Surgical practice changed from subtotal to lobectomies for benign goiter over a period of 17 years without change in laryngeal nerve damage but with increasing rates of postoperative hypocalcemia.

Keywords: goiter; subtotal resection; thyroidectomy.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Female
  • Goiter / surgery*
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / epidemiology*
  • Practice Patterns, Physicians' / trends*
  • Retrospective Studies
  • Thyroidectomy / methods*
  • Thyroidectomy / trends
  • Treatment Outcome
  • Young Adult