Patient with rapidly evolving neurological disease with neuropathological lesions of Creutzfeldt-Jakob disease, Lewy body dementia, chronic subcortical vascular encephalopathy and meningothelial meningioma

Neuropathology. 2017 Apr;37(2):110-115. doi: 10.1111/neup.12343. Epub 2016 Sep 16.

Abstract

We report a case of rapidly evolving neurological disease in a patient with neuropathological lesions of Creutzfeldt-Jakob disease (CJD), Lewy body dementia (LBD), chronic subcortical vascular encephalopathy and meningothelial meningioma. The coexistence of severe multiple pathologies in a single patient strengthens the need to perform accurate clinical differential diagnoses in rapidly progressive dementias.

Keywords: Creutzfeldt-Jakob disease; Lewy body dementia; chronic subcortical vascular encephalopathy; falcine meningioma; rapidly progressive Alzheimer's disease.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Brain / pathology
  • Brain / physiopathology
  • Brain Diseases / complications
  • Brain Diseases / diagnosis*
  • Brain Diseases / pathology*
  • Brain Diseases / physiopathology
  • Creutzfeldt-Jakob Syndrome / complications
  • Creutzfeldt-Jakob Syndrome / diagnosis*
  • Creutzfeldt-Jakob Syndrome / pathology*
  • Creutzfeldt-Jakob Syndrome / physiopathology
  • Disease Progression
  • Electroencephalography
  • Female
  • Humans
  • Lewy Body Disease / complications
  • Lewy Body Disease / diagnosis*
  • Lewy Body Disease / pathology*
  • Lewy Body Disease / physiopathology
  • Meningioma / complications
  • Meningioma / diagnosis*
  • Meningioma / pathology*
  • Meningioma / physiopathology
  • Neurologic Examination