[Role of radiotherapy in the treatment of NK/T-cell nasal type and primary cerebral lymphomas]

Cancer Radiother. 2016 Oct;20(6-7):535-42. doi: 10.1016/j.canrad.2016.07.078. Epub 2016 Sep 7.
[Article in French]

Abstract

The head and neck are common sites for extranodal non-Hodgkin lymphomas. Radiotherapy plays an important role in the treatment of low-grade lymphomas, with curative or palliative intent. In the case of high-grade lymphomas, its combination with chemotherapy is debated. Its role is however undeniable in two specific entities: NK/T-cell lymphoma NK/T nasal type, and primary central nervous system lymphomas, which are the subject of this review.

Keywords: Chemoradiotherapy; Chimioradiothérapie; High-dose methotrexate; Lymphome NK/T de type nasal; Lymphome cérébral primitif; Méthotrexate haute dose; NK/T-cell lymphoma nasal type; Primary CNS lymphoma; Radiotherapy; Radiothérapie.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Brain Neoplasms / therapy*
  • Chemotherapy, Adjuvant
  • Dementia / etiology
  • Humans
  • Lymphoma / therapy*
  • Lymphoma, Extranodal NK-T-Cell / therapy*
  • Methotrexate / therapeutic use
  • Neoplasm Recurrence, Local
  • Nose Neoplasms / therapy*
  • Prognosis
  • Radiotherapy Dosage
  • Radiotherapy, Adjuvant / adverse effects
  • Stem Cell Transplantation

Substances

  • Antineoplastic Agents
  • Methotrexate