Ophthalmic Manifestations in Chronic Inflammatory Rheumatic Diseases at a Referral Hospital of Yaounde, Cameroon

Ocul Immunol Inflamm. 2018;26(2):259-264. doi: 10.1080/09273948.2016.1212078. Epub 2016 Sep 6.

Abstract

Purpose: To determine the profile of ophthalmic manifestations in chronic inflammatory rheumatic diseases (CIRD).

Methods: Observational study at the Yaounde Central Hospital and Innel Medical Centre (2004 to 2012).

Results: The study population (n = 36) consisted of 14 men and 22 women with average age of 47.9 ± 17.2 years. Cases of CIRD were rheumatoid arthritis (n = 16), systemic lupus erythematosus (n = 8), ankylosing spondylitis (n = 8), mixed connective tissue disease (n = 2), scleroderma (n = 1), and juvenile idiopathic arthritis (n = 1). Ophthalmic manifestations found in 22 (61.1%) patients were dry eye syndrome (n = 7), cataract (n = 6), anterior uveitis (n = 6), glaucoma (n = 4), and suspected maculopathy (n = 1). No association was found between steroids used and supcapsular cataract (p = 0.06) or glaucoma (p = 0.06).

Conclusion: Ocular manifestations occurred in 61.1% of CIRD. Dry eye syndrome and anterior uveitis were commonly observed.

Keywords: Africa; anterior uveitis; cataract; chronic inflammatory rheumatic disease; corticoid; dry eye syndrome; glaucoma; suspected maculopathy.

MeSH terms

  • Adult
  • Cameroon / epidemiology
  • Cataract / diagnosis*
  • Chronic Disease
  • Dry Eye Syndromes / diagnosis*
  • Female
  • Glaucoma / diagnosis*
  • Humans
  • Male
  • Middle Aged
  • Referral and Consultation
  • Rheumatic Diseases / diagnosis*
  • Rheumatic Diseases / epidemiology
  • Uveitis, Anterior / diagnosis*