Myxofibrosarcoma

Christina L Roland; Wei-Lien Wang; Alexander J Lazar; Keila E Torres

doi:10.1016/j.soc.2016.05.008

Myxofibrosarcoma

Surg Oncol Clin N Am. 2016 Oct;25(4):775-88. doi: 10.1016/j.soc.2016.05.008. Epub 2016 Jul 30.

Authors

Christina L Roland¹, Wei-Lien Wang², Alexander J Lazar², Keila E Torres³

Affiliations

¹ Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1484, Houston, TX 77030, USA. Electronic address: clroland@mdanderson.org.
² Department of Pathology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 0085, Houston, TX 77030, USA.
³ Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1484, Houston, TX 77030, USA.

PMID: 27591498
DOI: 10.1016/j.soc.2016.05.008

Abstract

Myxofibrosarcoma is a unique subtype of soft tissue sarcoma with a locally infiltrative behavior. High-quality MRI imaging is critical for preoperative planning. Wide surgical resection with a 2 cm soft tissue margin is the mainstay of treatment and can require complex vascular and plastic surgery reconstruction. Local recurrence is common, and a subset of patients with higher-grade lesions will develop distant metastases. Radiation may be beneficial in reducing local recurrence.

Keywords: MRI; Myxofibrosarcoma; Recurrence; Surgery.

Publication types

Review

MeSH terms

Fibrosarcoma / diagnostic imaging*
Humans
Magnetic Resonance Imaging / methods*
Neoplasm Recurrence, Local / diagnosis
Neoplasm Recurrence, Local / diagnostic imaging*
Sarcoma / classification*
Soft Tissue Neoplasms / diagnostic imaging*