The effect of hypoxia and re-oxygenation on adipose tissue lipolysis in COPD patients

Andrea Plihalova; Hana Bartakova; Martina Vasakova; Sumeet Gulati; Isabelle deGlisezinski; Vladimir Stich; Jan Polak

doi:10.1183/13993003.00602-2016

The effect of hypoxia and re-oxygenation on adipose tissue lipolysis in COPD patients

Eur Respir J. 2016 Oct;48(4):1218-1220. doi: 10.1183/13993003.00602-2016. Epub 2016 Sep 1.

Authors

Andrea Plihalova¹, Hana Bartakova², Martina Vasakova³, Sumeet Gulati⁴, Isabelle deGlisezinski⁵, Vladimir Stich⁶, Jan Polak⁷

Affiliations

¹ 2nd Internal Medicine Department, Vinohrady Teaching Hospital, Prague, Czech Republic Center for Research on Diabetes, Metabolism and Nutrition, Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
² 1st Dept of Tuberculosis and Respiratory Diseases, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic.
³ Dept of Respiratory Medicine, First Faculty of Medicine, Charles University in Prague and Thomayer Hospital, Prague, Czech Republic.
⁴ Center for Research on Diabetes, Metabolism and Nutrition, Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
⁵ INSERM, UMR1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France University of Toulouse, UMR1048, Paul Sabatier University and Depts of Sports Medicine, Toulouse University Hospitals, Toulouse, France.
⁶ Center for Research on Diabetes, Metabolism and Nutrition, Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic Dept of Sports Medicine, Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
⁷ 2nd Internal Medicine Department, Vinohrady Teaching Hospital, Prague, Czech Republic Center for Research on Diabetes, Metabolism and Nutrition, Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic Dept of Sports Medicine, Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic jan.polak@lf3.cuni.cz.

PMID: 27587548
DOI: 10.1183/13993003.00602-2016

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adipose Tissue / metabolism
Atrial Natriuretic Factor / pharmacology
Epinephrine / pharmacology
Fatty Acids, Nonesterified / metabolism
Female
Humans
Hypoxia / metabolism*
Lipolysis* / drug effects
Male
Microdialysis
Middle Aged
Oxygen Inhalation Therapy
Pulmonary Disease, Chronic Obstructive / metabolism*
Pulmonary Disease, Chronic Obstructive / therapy
Severity of Illness Index
Subcutaneous Fat, Abdominal / drug effects
Subcutaneous Fat, Abdominal / metabolism*
Sympathomimetics / pharmacology

Substances

Fatty Acids, Nonesterified
Sympathomimetics
Atrial Natriuretic Factor
Epinephrine