Relationship among diet habit and lower urinary tract symptoms and sexual function in outpatient-based males with LUTS/BPH: a multiregional and cross-sectional study in China

Yuke Chen; Wei Yu; Liqun Zhou; Shiliang Wu; Yang Yang; Jianye Wang; Ye Tian; Dalin He; Yong Xu; Jian Huang; Xiaofeng Wang; Xin Gao; Hanzhong Li; Lulin Ma; Ning Zhang; Shengtian Zhao; Xunbo Jin

doi:10.1136/bmjopen-2015-010863

Relationship among diet habit and lower urinary tract symptoms and sexual function in outpatient-based males with LUTS/BPH: a multiregional and cross-sectional study in China

BMJ Open. 2016 Aug 31;6(8):e010863. doi: 10.1136/bmjopen-2015-010863.

Authors

Yuke Chen¹, Wei Yu¹, Liqun Zhou¹, Shiliang Wu¹, Yang Yang¹, Jianye Wang², Ye Tian³, Dalin He⁴, Yong Xu⁵, Jian Huang⁶, Xiaofeng Wang⁷, Xin Gao⁸, Hanzhong Li⁹, Lulin Ma¹⁰, Ning Zhang¹¹, Shengtian Zhao¹², Xunbo Jin¹³

Affiliations

¹ Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, National Urological Cancer Center, Beijing, China.
² Department of Urology, Beijing Hospital, Beijing, China.
³ Department of Urology, Beijing Friendship Hospital Affiliated with Capital Medical University, Beijing, China.
⁴ Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
⁵ Department of Urology, The Second Affiliated Hospital of Tianjin Medical University, Tianjin, China.
⁶ Department of Urology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, China.
⁷ Department of Urology, Peking University People's Hospital, Beijing, People's Republic of China.
⁸ Department of Urology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
⁹ Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
¹⁰ Department of Urology, Third Hospital of Peking University, Beijing, China.
¹¹ Department of Urology, Beijing Chao-yang Hospital Affiliated to Capital Medical University, Beijing, China.
¹² Department of Urology and Central Research Laboratory, Shandong University Second Hospital, Jinan, China.
¹³ Minimally Invasive Urology Center, Provincial Hospital Affiliated to Shandong University, Jinan, China.

Abstract

Objectives: This study assessed the effect of diet habits on lower urinary tract symptoms (LUTS) and sexual function in Chinese men with LUTS/benign prostatic hypertrophy (LUTS/BPH).

Setting: Multicentre study conducted between July 2013 and December 2013 in 11 hospitals in 3 geographic regions in China.

Participants: Overall, participants with LUTS/BPH accounted for 61.4% (2584/4208) of the respondents, whose data were processed in the following statistical analysis.

Primary and secondary outcome measures: LUTS and sexual function were assessed based on the International Prostate Symptom Score (IPSS) and the International Index of Erectile Function 5 (IIEF-5) score. Prostate volume (PV) was determined by ultrasound.

Results: A total of 4208 participants met the inclusion criteria. The average age of the whole participants was 65.8±7.7 years. Overall, participants with LUTS/BPH accounted for 61.4% (2584/4208) of the respondents, whose data were processed in the following statistical analysis. Generally, prostate enlargement was greatest in south China. LUTS and male sexual dysfunction (MSD) were most severe in northwest China. Based on multivariable analysis, PV enlarged as the age (p<0.001), body mass index (BMI; p<0.001) and vegetable intake (p<0.001) increased. Age (p<0.001) and BMI (p<0.05) independently increased the IPSS. A higher level of education (p<0.001) and more frequent meat, fish and egg intake (p<0.05) decreased the IPSS. Age (p<0.001), BMI (p<0.001), low education level (p<0.05), vegetable intake (p=0.001), and milk and dairy product intake (p=0.001) decreased the IIEF-5 score.

Conclusions: In addition to factors including age, obesity and level of education, dietary habits and geographic difference might also play an important role in the variation of PV, LUTS and MSD for Chinese men with LUTS/BPH.

Keywords: China; diet habit; lower urinary tract symptoms; prostate volume; sexual function.

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Publication types

Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Aged
China / epidemiology
Cross-Sectional Studies
Diet*
Educational Status
Erectile Dysfunction / epidemiology*
Humans
Linear Models
Lower Urinary Tract Symptoms / complications*
Lower Urinary Tract Symptoms / physiopathology
Male
Middle Aged
Multivariate Analysis
Outpatients / statistics & numerical data*
Prostatic Hyperplasia / complications*
Prostatic Hyperplasia / physiopathology
Severity of Illness Index