Erecricins A-E, prenylated acylphloroglucinols from the roots of Hypericum erectum

Abstract

Six new prenylated acylphloroglucinols, erecricins A-E (1-5) and adotogirin (6), were isolated from the roots of Hypericum erectum (Hypericaceae). Their structures were assigned on the basis of spectroscopic evidences. Erecricins A-E (1-5) are bicyclic prenylated acylphloroglucinols possessing a chromane or a chromene skeleton. Adotogirin (6) is a simple achylphloroglucinol with an O-geranyl moiety. Antimicrobial activities of these acylphloroglucinols were also evaluated.

Keywords: Acylphloroglucinol; Adotogirin; Erecricins A–E; Hypericaceae; Hypericum erectum.