Evaluation of a Rapid Lateral Flow Point-of-Care Test for Detection of Cryptosporidium

Molly E Fleece; Jack Heptinstall; Shaila S Khan; Mamum Kabir; Joel Herbein; Rashidul Haque; William A Petri

doi:10.4269/ajtmh.16-0132

Evaluation of a Rapid Lateral Flow Point-of-Care Test for Detection of Cryptosporidium

Am J Trop Med Hyg. 2016 Oct 5;95(4):840-841. doi: 10.4269/ajtmh.16-0132. Epub 2016 Aug 29.

Authors

Molly E Fleece¹, Jack Heptinstall², Shaila S Khan³, Mamum Kabir³, Joel Herbein², Rashidul Haque³, William A Petri¹

Affiliations

¹ Department of Medicine, University of Virginia, Charlottesville, Virginia.
² TechLab, Inc., Blacksburg, Virginia.
³ International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.

Abstract

A new rapid lateral flow fecal antigen detection test for Cryptosporidium was evaluated using diarrheal stool samples from a cohort of children in Bangladesh. The test had a sensitivity of 100% and a specificity of 94% when compared with enzyme-linked immunosorbent assay antigen detection.

Publication types

Evaluation Study

MeSH terms

Antibodies, Monoclonal / immunology*
Antigens, Protozoan / analysis*
Bangladesh
Chromatography, Affinity
Cohort Studies
Cryptosporidiosis / diagnosis*
Cryptosporidiosis / parasitology
Cryptosporidium / immunology*
Cryptosporidium / isolation & purification
Diarrhea / diagnosis*
Diarrhea / parasitology
Enzyme-Linked Immunosorbent Assay
Feces / parasitology
Humans
Infant
Point-of-Care Testing*
Sensitivity and Specificity

Substances

Antibodies, Monoclonal
Antigens, Protozoan

Abstract

Publication types

MeSH terms

Substances

Grants and funding