Curative potential of allogeneic hematopoietic stem cell transplant in type 1 diabetes

Kristen E McCabe; Allison J Pollock; Jennifer L Rehm; Kenneth B DeSantes

doi:10.1111/pedi.12430

Curative potential of allogeneic hematopoietic stem cell transplant in type 1 diabetes

Pediatr Diabetes. 2017 Dec;18(8):832-834. doi: 10.1111/pedi.12430. Epub 2016 Aug 30.

Authors

Kristen E McCabe¹, Allison J Pollock¹, Jennifer L Rehm¹, Kenneth B DeSantes¹

Affiliation

¹ Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

Abstract

The mainstay of treatment for type 1 diabetes (T1D) is exogenous insulin. Here, we report a case in which exogenous insulin requirements were eliminated after an allogeneic hematopoietic stem cell transplant for aplastic anemia in a pediatric patient recently diagnosed with T1D, and explore the validity of this approach compared with current treatments.

Keywords: aplastic anemia; autoimmune; transplant; type 1 diabetes.

Publication types

Case Reports

MeSH terms

Adolescent
Diabetes Mellitus, Type 1 / therapy*
Hematopoietic Stem Cell Transplantation*
Humans
Male
Transplantation, Homologous

Grants and funding

T32 DK077586/DK/NIDDK NIH HHS/United States