Intralesional triamcinolone injections for the treatment of preauricular sinus infections

Am J Otolaryngol. 2016 Nov-Dec;37(6):523-527. doi: 10.1016/j.amjoto.2016.08.002. Epub 2016 Aug 5.

Abstract

Objectives: The aim of this study is to confirm the effect of adjuvant intralesional triamcinolone acetonide injections (TRIAM) for the treatment of an infected preauricular sinus (PAS).

Methods: The medical charts of 103 patients diagnosed with PAS from March 2013 to December 2015 were reviewed and documented. The mean duration of treatment and postoperative follow-up period were compared between patients who received TRIAM and patients who received conventional treatment.

Results: Fifteen patients received TRIAM. The mean duration of treatment was 12.5±11.0days in patients treated with TRIAM, which was significantly shorter than patients without TRIAM (25.5±25.7days, p=0.010). In addition, the percentage of patients experiencing early recovery (within 10days) was 4.15 times higher with TRIAM (95% confidence interval: 1.07-16.13, p=0.040). The mean postoperative follow-up period revealed a similar tendency; patients treated with TRIAM required a shorter follow-up period (8±2.6days) than patients not treated with TRIAM (13.5±7.4days). However, this difference was not significant (p=0.242).

Conclusion: Although the sample was small, patients with PAS infections who were treated with TRIAM as an adjuvant therapy required a significantly shorter treatment duration than patients receiving conventional treatment alone. This finding suggests a beneficial effect of TRIAM for the short-term control of PAS infections. Clinicians should consider TRIAM as an adjuvant treatment option.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Combined Modality Therapy
  • Ear Auricle / abnormalities*
  • Ear Auricle / microbiology
  • Ear Auricle / surgery
  • Female
  • Glucocorticoids / administration & dosage*
  • Humans
  • Infant
  • Injections, Intralesional
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome
  • Triamcinolone Acetonide / administration & dosage*
  • Young Adult

Substances

  • Glucocorticoids
  • Triamcinolone Acetonide