Management of Breast Sarcoma

Cary Hsu; Susan A McCloskey; Parvin F Peddi

doi:10.1016/j.suc.2016.05.004

Management of Breast Sarcoma

Surg Clin North Am. 2016 Oct;96(5):1047-58. doi: 10.1016/j.suc.2016.05.004.

Authors

Cary Hsu¹, Susan A McCloskey², Parvin F Peddi³

Affiliations

¹ Department of Surgery, Baylor College of Medicine, One Baylor Plaza, MS 390, Houston, TX 77030, USA. Electronic address: Cary.Hsu@bcm.edu.
² Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
³ Division of Hematology & Oncology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

PMID: 27542642
DOI: 10.1016/j.suc.2016.05.004

Abstract

Breast sarcomas are exceptionally rare mesenchymal neoplasms composed of many histologic subtypes. Therapy is guided by principles established in the management of extremity sarcomas. The anatomic site does influence treatment decisions, particularly the surgical management. Surgery should be undertaken with the aim of achieving a widely negative margin. Selected patients can be managed with breast-conserving surgery. Breast reconstruction is increasingly being undertaken for selected patients. Radiation therapy and chemotherapy are used selectively for large, high-grade sarcomas for which there is significant concern for local and distant recurrence.

Keywords: Breast; Chemotherapy; Multidisciplinary; Radiation; Sarcoma; Surgery.

Publication types

Review

MeSH terms

Breast Neoplasms / therapy*
Combined Modality Therapy
Disease Management*
Female
Humans
Sarcoma / therapy*