[Update to the recommendations for management of melanoma stages I to III]

Ann Dermatol Venereol. 2016 Oct;143(10):629-652. doi: 10.1016/j.annder.2016.07.001. Epub 2016 Aug 12.
[Article in French]

Abstract

As knowledge continues to develop, regular updates are necessary concerning recommendations for practice. The recommendations for the management of melanoma stages I to III were drawn up in 2005. At the request of the Société Française de Dermatologie, they have now been updated using the methodology for recommendations proposed by the Haute Autorité de Santé. In practice, the principal recommendations are as follows: for staging, it is recommended that the 7th edition of AJCC be used. The maximum excision margins have been reduced to 2cm. Regarding adjuvant therapy, the place of interferon has been reduced and no validated emerging medication has yet been identified. Radiotherapy may be considered for patients in stage III at high risk of relapse. The sentinel lymph node technique remains an option. Initial examination includes routine ultrasound as of stage II, with other examinations being optional in stages IIC and III. A shorter strict follow-up period (3years) is recommended for patients, but with greater emphasis on imaging.

Keywords: Classification; Management; Melanoma; Mélanome; Prise en charge; Recommandations; Recommendations; Staging.

Publication types

  • Practice Guideline
  • Review

MeSH terms

  • Biomarkers, Tumor / analysis
  • Chemotherapy, Adjuvant
  • Diagnostic Imaging
  • Genetic Counseling
  • Humans
  • Immunohistochemistry
  • Lymphatic Metastasis
  • Margins of Excision
  • Melanoma / pathology*
  • Melanoma / therapy*
  • Neoplasm Staging
  • Radiotherapy, Adjuvant
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / therapy*

Substances

  • Biomarkers, Tumor