Abstract
Six polyphenolic acids (1-6), including the three new compounds citriodolic acids A, B, and C (1-3), were isolated from the leaves of Eucalyptus citriodora. Their structures were elucidated by spectroscopic methods including one dimensional (1D)- and 2D-NMR, high-resolution electrospray ionization (HR-ESI)-MS, and circular dichroism (CD). The potential antivirus activity against respiratory syncytial virus (RSV) of all the isolated compounds was evaluated.
MeSH terms
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Antiviral Agents / chemistry
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Antiviral Agents / isolation & purification
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Antiviral Agents / pharmacology*
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Caffeic Acids / chemistry
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Caffeic Acids / isolation & purification
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Caffeic Acids / pharmacology*
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Dioxanes / chemistry
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Dioxanes / isolation & purification
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Dioxanes / pharmacology*
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Dose-Response Relationship, Drug
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Eucalyptus / chemistry*
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Microbial Sensitivity Tests
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Molecular Conformation
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Plant Leaves / chemistry*
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Polyphenols / chemistry
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Polyphenols / isolation & purification
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Polyphenols / pharmacology*
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Respiratory Syncytial Viruses / drug effects*
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Structure-Activity Relationship
Substances
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Antiviral Agents
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Caffeic Acids
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Dioxanes
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Polyphenols
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citriodolic acid A
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citriodolic acid B
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citriodolic acid C